The IRCCS* San Raffaele Hospital in Milan is an internationally renowned clinical science university hospital with outstanding, highly specialized health care offerings. Since opening in 1971, the IRCCS SAN RAFFAELE has made patient care, a commitment to research, and innovation its top priorities, allowing it to provide incomparable benefits to general health care and research.

* IRCCS means “Istituto di Ricovero e Cura a Carattere Scientifico” , Scientific Institutes for Research, Hospitalization and Health Care. IRCCS are independent institutions of national relevance working according to standards of excellence in order to perceive research aims, mainly clinical and translational, in the bio-medical field as well as in the organization and management of sanitary services, with special reference to highly specialized hospitalization and health care

The IRCCS SAN RAFFAELE is a hospital accredited by the Italian National Health Service that offers specialized treatments for 49 health specialties. Located in the north east area of Milan, San Raffaele Hospital encompasses roughly 30 hectares and retains more than 6,000 employees. Other related structures are the private, not-for-profit San Raffaele Turro Hospital, Cardinal Schuster Polyclinic Hospital, and San Donato Milanese Clinic, which together house 1,373 hospital beds. Annually, these various sites performers more than 25,000 surgeries, had more than 63,500 emergency rooms admissions, 43,000 hospitalizations, and 7 million among outpatient admissions and laboratory tests.

San Raffaele Hospital is also accredited as a clinic-didactic hospital (University Vita-Salute San Raffaele) that offers internationally recognized courses in medical specialization within the Faculty of Medicine and Psychology, as well as degree courses for all health-related professions. In 2010, the Master of Science in International Medicine and International Medical Doctor Surgery Program, the only medicine program in Europe, began licensing medical doctors to practice in both European and North American countries.

National and International certifications

The most important priorities of San Raffaele Hospital are patients and their families, on whose needs the hospital has always focused its energies and attention by continually improving the quality of health care services. In the last decade, the quality of the hospital’s management, staff, and departments have been recognized by:

  • The International Organization for Standardization (European certification, UNI EN ISO 9000:2000)
  • National Institutional Accreditation
  • The National Observatory for Women’s Health Care (O.N.Da)
  • Good Laboratory Practice (GLP)

The Management System for the Quality of San Raffaele Hospital is certified according to the international standard UNI EN ISO 9001: 2008 (Certificate No. 9122.SRAF) was issued by IMQ-CSQ, the world’s leading certification company. The purpose of this certification is to ensure high-quality care offerings and patient access to management and greater accuracy in health care and research performance for the benefit of national and international patients. This general system of quality management has certified the entire organization, including cross-administrative areas, the health and clinical sectors and the research sector.

Since 2007, San Raffaele Hospital has been accredited by the National Observatory for Women’s Health Care (O.N.Da), whose goal is to identify, connect, and reward hospitals that offer care and social services dedicated to the prevention, diagnosis, and treatment of women’s diseases.

The San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET) has obtained certification to perform preclinical testing and support the development and registration of gene therapy, in accordance with the principles of Good Laboratory Practice (GLP).

In 2013, UNICEF-OMS accredited San Raffaele Hospital as a baby-friendly hospital as part of a worldwide initiative to improve the care of pregnant women, mothers, and newborns at health facilities and to provide maternity services for protecting, promoting, and supporting breastfeeding.

San Raffaele Hospital is also accredited by the Joint Accreditation Committee’s International Society for Cellular Therapy (ISCT) and the European Society for Blood and Marrow Transplantation (EBMT), which promote high-quality patient care and laboratory performance in hematopoietic stem cell collection, processing, and transplantation centers via the development of global standards and an internationally recognized system of accreditation.


IRCCS at San Raffaele Hospital provides 49 health specialties within 12 main departments:

  • Cardio-Thoracic-Vascular Department
  • General and Special Surgery Department
  • Head and Neck Department
  • Infectious Diseases Department
  • Mother and Child Care Department
  • Internal Medicine Department
  • Neurology Department
  • Clinical Neurosciences Department
  • Oncology Department
  • Medical Oncology Department
  • Urology Department
  • Radiology Department

Surgeons in the Urology Department, in collaboration with colleagues from other specialties, manage one of the largest genitourinary cancer patient populations in the country. All types of genitourinary cancer as well as nonmalignant tumors of the urinary tract and male reproductive system are evaluated and treated here.

The Urology Department emphasizes multimodal therapy, including complex surgical procedures, with careful attention to quality-of-life issues. Every treatment plan considers how normal body functions can be maintained. Selected surgeons in the department perform minimally invasive surgery, including cryosurgical, laparoscopic and robotic procedures.


IRCCS at San Raffaele Hospital integrates compassionate care with state-of-the-art research and rigorous medical training. In the Neurology Department, expert specialty care is aided by the latest medical technology—from life-saving intervention for acute brain trauma to skillful management of chronic illnesses. The department retains medical doctors, surgeons, and research specialists dedicated to the treatment of adult and pediatric patients with neurological and psychiatric disorders by offering disease-specific, patient-focused approaches to care.

The Neurology Department’s specialists allow patients to better access the care they need through specialized, multidisciplinary, disease-specific centers that integrate the expertise of neurologists, neurosurgeons, psychiatrists, psychologists, neuroradiologists, and others, into the comprehensive care of a single disease, to provide care and treatments for an array of neurological disorders.


The cardiologists, cardiac surgeons, interventional radiologists, and vascular surgeons at IRCCS work together to provide high-quality, comprehensive care and the latest innovations in cardiac care and clinical therapies to patients of all ages. They provide state-of-the-art tests and procedures to provide accurate diagnoses and create treatment plans.

The Cardio-Thoracic-Vascular Department treats patients with common heart problems such as angina, artery problems, valvular heart disease, and heart failure, as well as patients with very rare forms of heart disease.

The department performs roughly 1,400 cardiac surgeries each year, covering the widest spectrum of cardiac surgical disciplines and procedures, as an international center for the surgical repair of the mitral valve (about 500 operations by year), in addition to surgeries for atrial fibrillation and heart failure. It is also a national reference center for open-heart coronary surgery.

The Cardio-Thoracic-Vascular Department also serves patients with cancers arising in the chest and involving pulmonary, esophageal, and mediastinal tumors, as well as metastases to the chest from other tumor sites. Its efforts are directed at improving treatment results by using minimally invasive techniques and combining surgery with chemotherapy, radiation therapy, gene therapy, and novel therapeutics.


Within the Oncology and Medical Oncology Department, two main operative units are nationally and internationally recognized for providing comprehensive health care and top-quality treatments:


The Onco-Hematopathology Unit provides diagnostic services and specialized testing for patients with all types of leukemia, lymphoma, and benign hematologic disorders. It specializes in the diagnosis of a range of hematological disorders, including:

  • Acute and chronic leukemia
  • Myelodysplastic syndromes
  • Myeloproliferative disorders
  • Anemia
  • Benign bone marrow and T-cell lymphomas
  • Cutaneous lymphomas

The Onco-Hematopathology Unit is a reference center for the research and treatment of chronic lymphocytic leukemia within the European Leukemia Net, a network of European centers that study and treat leukemia, such as ERIC (the European Research Initiative on Chronic Lymphocytic Leukemia), the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) and Chronic Lymphocytic Leukemia Global Research Foundation (MD Anderson Cancer Center, Houston, USA).


The Nuclear Medicine Operative Unit performs investigations of both conventional nuclear medicine with positron emission tomography (PET) for patients in Lombardy and from other regions in Italy. It retains two cyclotrons for the production of PET tracers and four tomography PET / CT approaches for oncological, neurological, and cardiological study.

IRCCS is currently the leading Italian institute for health care offerings and clinical research in terms of volume and scientific research contributions; in 2012, it published 1,107 studies, of which nearly 8% appeared in scientific journals of the most qualified international level of impact (i.e., an impact factor exceeding 10).

San Raffaele’s scientific research comes from a multidisciplinary context of a number of divisions, institutes, and research centers that operate in all fields of biomedical and health research and which encompass ​​over 130,000 m2 of laboratories and facilities. Its numerous collaborations with leading international research centers place San Raffaele Hospital at the forefront of biomedical research.

The mission of the IRCCS is therefore to advance research, promote progress in the knowledge of human diseases, identify new therapies to benefit patients, and create an environment more favorable to the growth of a new generation of scientists and doctors.

IRCCS is characterized by top-level breakthroughs in basic, translational, and clinical research, whose and a profound integration and cooperation between these three areas in order to achieve groundbreaking levels of health care quality and clinical trial programs.